Adrenal glands are located above kidneys, measuring 5x3x1 cm and weighing 7-10g. Each gland has outer cortex and inner medulla. Cortex divided into three zones: glomerulosa, fasciculata, and reticularis. Medulla produces catecholamines (adrenaline and noradrenaline)
Cortisol is a steroid hormone produced by adrenal cortex's zona fasciculata. Released in diurnal cycle in response to stress and low blood glucose. Used medically as hydrocortisone
Test measures cortisol secretion suppression by adrenal gland. Two types: low-dose (1mg/day) and high-dose (8mg/day). Can be done overnight or standard (3-day) method
Cortisol is produced naturally to respond to stress. High cortisol levels can lead to weakened immune system and health problems. Cortisol levels naturally rise in morning and lowest around midnight
Cortisol is a stress hormone produced by adrenal glands. Normal cortisol levels peak in morning and decline throughout day. High cortisol can lead to fatigue, anxiety and sleep disturbances
Cushing syndrome occurs when body produces excessive cortisol. Can result from excessive cortisol production or glucocorticoid medication. Treatment aims to lower cortisol levels and improve symptoms