Carpal tunnel is a flattened cavity on flexor side of wrist. Forms passageway for median nerve and flexor muscle tendons. Narrowest section is 1.6 cm2 beyond mid-line of distal carpal bones. Flexor retinaculum covers sulcus carpi on palmar side
Vitamin B6 consists of pyridoxine, pyridoxal, and pyridoxamine derivatives. The metabolically active form is pyridoxal 5'-phosphate (P5P). P5P is the main circulating form and most relevant measure of B6 status
NCS evaluates motor and sensory nerve function through electrical conduction. Test performed by specialists like neurophysiologists and physical therapists. Patients typically don't need special preparation, except avoiding skin creams. Test combines with needle electromyography for comprehensive evaluation
Median nerve originates from brachial plexus' lateral and medial cords. Enters arm from axilla, passes through cubital fossa. Only nerve passing through carpal tunnel. Supplies muscles of forearm and hand
The forearm consists of two long bones: radius and ulna. The radius articulates with the ulna and scaphoid/lunate bones. The ulna articulates with the radius and the wrist's triangular fibrocartilage disc. The bones are connected by the interosseous membrane
Carpal tunnel causes tingling and weakness in wrists due to median nerve compression. More common in women, especially during pregnancy. Can be worsened by diabetes, obesity, and rheumatoid arthritis