Scrotal cysts, also known as epidermal or sebaceous cysts, are benign sacs filled with fluid that can develop in the scrotum, the pouch of skin that holds the testicles. Types of scrotal cysts: Epididymal cysts. Sebaceous cysts. Causes of scrotal cysts: blockage of sebaceous glands; injury or trauma; genetic factors; infection. Symptoms: often no symptoms; swelling around the scrotum; lump or mass in the scrotum; pain or discomfort, especially with larger growths; redness or inflammation of the scrotal area. Treatment options: observation; medication, such as nonsteroidal anti-inflammatory drugs (NSAIDs); minimally invasive therapies, such as aspiration or sclerotherapy; surgery. If a scrotal cyst is noticed, it is essential to consult a healthcare provider for a physical examination to rule out other conditions.