Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii parasite. Disease affects both cats and their human owners. Can cause brain abnormalities in newborns and eye problems in children. Most healthy humans become immune after exposure
Toxoplasmosis is caused by Toxoplasma gondii, a parasitic apicomplexan. Disease spreads through eating undercooked meat, cat feces, or during pregnancy. Up to half of world's population is infected but asymptomatic. Three types exist: I (virulent in mice and humans), II (virulent in humans), III (less severe)
Corin is a 1042-amino-acid protein encoded by the CORIN gene. Contains transmembrane, cytoplasmic, and extracellular domains. Synthesized as a zymogen activated by PCSK6. Exhibits trypsin-like catalytic activity favoring basic residues. Contains 19 N-glycosylation sites for cell surface expression
First identified in Uganda in 1947, spread to Africa and Asia in 1950s. Global outbreaks since 2007 in Africa, Americas, Asia and Pacific. First cases reported in Europe in 2019, India in 2021. Currently affects 89 countries with limited global surveillance
Mugwort is a perennial plant native to Europe, Asia, and Africa. Used in traditional medicine worldwide. Promoted for digestive problems, irregular menstruation, and high blood pressure
About 11% of US population is seropositive to Toxoplasma gondii. Cats are only definitive hosts, transmitting oocysts through feces. Humans can contract through contaminated food, water, or undercooked meat