Tricyclic antidepressants (TCAs) are a class of medications used to treat depression and other conditions such as anxiety disorders, chronic pain, and migraine. How they work: TCAs increase the levels of serotonin and norepinephrine in the brain, which are neurotransmitters that affect mood. Examples of TCAs: Amitriptyline, desipramine, doxepin, imipramine, nortriptyline, protriptyline. Possible side effects: Drowsiness, blurred vision, constipation, dry mouth, weight gain, increased sweating, sexual problems, and others. Precautions: TCAs can interact with other medications and supplements, so it is important to inform the doctor about all taken drugs. Overdose: TCAs can be dangerous if taken in excess, so it is necessary to follow the doctor's recommendations and not stop taking the medication suddenly.