Life-threatening condition obstructing small liver veins. Common after chemotherapy before bone marrow transplant. Can occur from pyrrolizidine alkaloids in herbal teas. May be hereditary from SP110 gene mutations
CHOP's Immune Dysregulation Program manages various forms of HLH. Comprehensive team includes specialists from multiple medical departments. Program aims to calm inflammation and prevent damage
Neurologic complications occur in 3-44% of HSCT recipients. Complications can be life-threatening and challenging to manage. Early complications often result from conditioning regimen drugs
Blood stem cells produce billions of new blood cells daily. Stem cells constantly divide and replace worn-out blood cells. Cancer treatments can destroy stem cells, requiring transplantation
Bone marrow is the spongy tissue located in bone cavities. More bone marrow is found in larger bones like hips. Contains fat, stem cells, and blood vessels
HLA typing matches patients and donors for bone marrow, cord blood, or organ transplants. HLA system is a group of genes forming major histocompatibility complex (MHC). HLA proteins help immune system identify body cells