Lixiana contains edoxaban tosylate, approved in EU on June 19, 2015. Used to prevent stroke and systemic embolism in atrial fibrillation patients. Treats and prevents DVT and pulmonary embolism in adults. Available as 15, 30, and 60 mg tablets, taken once daily
Treats metastatic colorectal cancer after chemotherapy and anti-VEGF therapy. Approved for GIST after imatinib and sunitinib treatment. Used for HCC after sorafenib treatment. Recommended daily dose is 160 mg for 21 days of each 28-day cycle
Rivaroxaban should not be used with other anticoagulants. Increased bleeding risk occurs with all anticoagulant combinations. Monitoring for blood loss is essential during treatment
Developed in 2010 for assessing major bleeding risk in AF patients. Based on data from 3,978 people in Euro Heart Survey. Used with CHA2DS2-VASc score for bleeding risk assessment
Cranberries are low, evergreen shrubs up to 2 meters long. Dark pink flowers with reflexed petals, edible berries turning red when ripe. Four-five species exist, with Vaccinium oxycoccos in Europe and V. macrocarpon in North America
About 40% of PCI patients are at high bleeding risk (HBR). HBR patients had 6.4% bleeding risk vs 1.9% in non-HBR patients. HBR patients had 12.5% composite endpoint vs 6.1% in non-HBR patients. ARC-HBR criteria showed higher sensitivity but lower specificity than other scores