60-70% of thrombosis patients have specific inherited thrombophilia. Factor V Leiden mutation affects 3-8% of White adults, increasing risk 5x. Antithrombin deficiency occurs in 1/2000-5000 population. Protein C deficiency affects 1/60-300 healthy adults
Factor V Leiden is a genetic disorder causing increased blood clotting. Most common hereditary hypercoagulability disorder among ethnic Europeans. About 5% of Caucasians in North America have this condition
Cardiology is a medical specialty dealing with heart issues. Treats conditions like coronary artery disease, heart failure, and valve problems. Includes subspecialties like electrophysiology, echocardiography, and nuclear cardiology
DVT is the most common type of venous thromboembolism. Blood clot forms in deep veins, usually in lower leg or pelvis
WPW is a congenital heart defect present at birth. Extra pathway between heart chambers causes fast heartbeat. Condition may occur with other congenital heart defects. Can be inherited or occur with hypertrophic cardiomyopathy
Guidelines developed by ACC/AHA and ESC committees for ventricular arrhythmias. Published in September 2006 in major cardiovascular journals. Aims to combine existing guidelines into single source. Streamlined document with minimum wording for clinical presentations