Short stature occurs when child's height is below average for age, sex, and race. Height is measured using anthropometric tools and compared to standard measurements. Height falls in 2.3rd percentile or below 3rd percentile of mean
Endometriosis grows in womb areas, affecting ovaries, tubes, bladder and bowel. Severe period pain and heavy bleeding occur during menstruation. Other symptoms include pelvic pain, sex pain, fatigue and fertility issues. Condition affects women from puberty to menopause
Lenvatinib is a receptor tyrosine kinase inhibitor for various cancers. Targets VEGFR1, VEGFR2, and VEGFR3 receptors in cancer cells. Also inhibits FGF, PDGFRα, KIT, and RET receptors. Binds to VEGFR2 via cyclopropane ring to inhibit kinase activity
Male infertility affects approximately 7% of all men worldwide. Sperm quality declines significantly with age, especially after 36. Antisperm antibodies affect 10-30% of infertile couples. Chromosomal anomalies and genetic mutations cause 10-15% of cases
Genetic disorder preventing puberty completion. Characterized by total or reduced sense of smell. Affects both males and females, with 4x higher incidence in males. Causes infertility and increased risk of osteoporosis
Virilization refers to male characteristics development in young individuals. Prenatal virilization involves penis growth and urethral groove closure. XX chromosomes can develop virilization, XY chromosomes can undervirilize. SRY gene was previously believed to control female development