MCTD was first described by Sharp et al. in 1972. Disease shares characteristics with multiple autoimmune conditions. Term introduced by Leroy in 1980
Myocardial infarction occurs when blood flow to heart muscle stops, causing tissue death. Most common symptom is chest pain radiating to left shoulder, arm or jaw. Other symptoms include shortness of breath, nausea, and feeling faint. About 30% of people have atypical symptoms. Women often present without chest pain, often with neck or arm pain
Appendicitis causes right lower abdominal pain, nausea, vomiting and decreased appetite. Approximately 40% of people don't have typical symptoms. Diagnosis relies on physical exam, blood tests and imaging. Ultrasound is preferred in children and pregnant women. CT scan is more accurate than ultrasound for diagnosis
Common cold affects nose and throat, caused by viruses. Most people recover in 7-10 days without medical care. Adults typically get 2-3 colds yearly, children more frequently
Paleness is a sign of a problem, not just natural lightening. It can affect any skin tone and cause whitening of mucous membranes. Paleness is caused by inadequate blood supply or low red blood cells
Cold sweats (diaphoresis) are sudden sweating unrelated to heat or exertion. Normal sweating is body's cooling mechanism, cold sweats aren't. Cold sweats aren't treated directly, healthcare focuses on underlying causes