Paroksismal noktürnal hemoglobinüri (PNH), kemik iliğindeki kan yapıcı kök hücrelerde yaşanan edinilmiş bir genetik mutasyon sonucu ortaya çıkar. PNH'ye neden olan mutasyon genellikle PIG-A geninde gerçekleşir.
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paroksismal noktürnal hemoglobinüri anlamına gelir [```1```](https://thd.org.tr/thdData/userfiles/file/PNH(1).pdf)[```2```](https://aa-pnh.org/tr/hastaliklar/pnh/)[```5```](https://tr.wikipedia.org/wiki/Paroksismal_nokturnal_hemoglobin%C3%BCri). \n\n**PnH** ise bu hastalığın kısaltması olarak kullanılabilir [```3```](https://kolaysaglik.net/paroksismal-nokturnal-hemoglobinemi-pnh/).","sources":[{"sourceId":1,"url":"https://www.merriam-webster.com/medical/PNH","title":"PNH Definition & Meaning | Merriam-Webster Medical","shownUrl":"https://www.merriam-webster.com/medical/PNH","rel":"nofollow"},{"sourceId":2,"url":"https://www.aamds.org/pnh","title":"Paroxysmal Nocturnal Hemoglobinuria (PNH) | Aplastic...","shownUrl":"https://www.aamds.org/pnh","rel":"nofollow"},{"sourceId":3,"url":"https://tr.wikipedia.org/wiki/Paroksismal_nokturnal_hemoglobin%C3%BCri","title":"Paroksismal Nokturnal Hemoglobinüri - 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