Group A Streptococcus found mainly in throat and pharynx. Group B Streptococcus primarily resides in digestive tract
Single course recommended for 24-33.6 weeks gestation at risk of preterm delivery. Betamethasone may be considered for 34-36 weeks gestation at risk. Rescue course possible as early as 7 days after initial dose. Regular repeat courses not recommended due to safety concerns
Global maternal mortality ratio aims for 70 deaths per 100,000 births by 2030. Neonatal mortality target is 12 deaths per 1,000 live births. AIDS, tuberculosis, malaria and neglected tropical diseases must be ended. Non-communicable diseases mortality target is 33% reduction by 2030
PPROM occurs before 37 weeks gestation before labor onset. All women should be hospitalized for 72 hours. Delivery recommended when infection risk outweighs prematurity risk. Some patients may be managed outpatient under close supervision
Neonatal sepsis is bacterial bloodstream infection in newborns with fever. Divided into early-onset (first 7 days) and late-onset (after 7 days). Most common cause of neonatal death in developing countries
Perinatal mortality refers to deaths of fetuses or neonates during first 28 days. WHO defines it as deaths per 1,000 births, starting at 22 weeks gestation. UK rate is about 8 per 1,000 births, highest in Asian women