Blood clot travels through bloodstream causing tissue ischemia. VTE includes deep vein thrombosis and pulmonary embolism. Main treatment is anticoagulation to prevent thrombus propagation. Direct oral anticoagulants offer safer alternative to conventional treatments. Treatment duration varies based on risk factors and patient characteristics
DVT is blood clot formation in deep veins, most commonly in legs or pelvis. Symptoms include pain, swelling, redness, and enlarged veins. Some DVTs may have no symptoms
PE is partial or complete occlusion of pulmonary arteries due to thrombus. Non-thrombotic sources include gas, fat, tumor, and foreign bodies. Classified based on hemodynamic compromise, temporal pattern, and symptoms
High-risk PE causes acute right ventricular failure and hypoxia. Most deaths occur within first hour after presentation. CT angiography provides segmental visualization and RV enlargement. Echocardiography confirms or excludes severe RV dysfunction
Atrial fibrillation: 60 mg daily for stroke prevention. DVT/PE: 60 mg daily after 5-10 days of parenteral anticoagulation. Weight-based dosing: 30 mg daily for patients under 60 kg
Pericarditis shows diffuse ST elevation and PR depression in all leads. Spodick's sign is seen in 80% of pericarditis patients. STEMI differs from pericarditis by having convex or horizontal ST elevation