Kell antigen system determines blood type and targets for autoimmune diseases. System includes K, k, Kpa, Kpb, Jsa and Jsb antigens. Kell protein is a 93-kilodalton zinc-dependent endopeptidase. KEL gene encodes type II transmembrane glycoprotein
ITP is an autoimmune disorder characterized by low platelet count without other causes. Children have acute form, adults have chronic form. Approximately 60% of cases show platelet antibody detection
MCTD was first described by Sharp et al. in 1972. Disease shares characteristics with multiple autoimmune conditions. Term introduced by Leroy in 1980
Pancytopenia is low levels of all blood cell types in bone marrow. Includes anemia (low RBCs), leukopenia (low WBCs), and thrombocytopenia (low platelets). All blood cells originate from hematopoietic stem cells
Immunosuppressants block immune system parts to treat autoimmune diseases and organ transplants. Treatments include traditional drugs like corticosteroids and biologics like Humira. Used for conditions like psoriasis, Crohn's, multiple sclerosis, and organ transplants. Common in cancer treatment as side effect of chemotherapy and radiation
More than 24 million Americans have autoimmune diseases. AIP diet modifies Paleolithic diet to eliminate modern processed foods. Diet aims to reduce or relieve autoimmune-related symptoms