DVT is blood clot formation in deep veins, most commonly in legs or pelvis. Symptoms include pain, swelling, redness, and enlarged veins. Some DVTs may have no symptoms
Blood flow to spleen is compromised, leading to tissue death. Typical symptom is severe left upper quadrant pain, sometimes radiating to shoulder. Fever and chills may develop in some cases. Mortality rate in 59 patients is 5%
Anticoagulants prevent blood clotting and are used in thrombotic disorders. Warfarin and heparin are common anticoagulants used in medical settings. Newer direct oral anticoagulants (DOACs) offer fewer side effects than warfarin
Lupus anticoagulant is an immunoglobulin that binds to cell membrane phospholipids. In vitro, it increases coagulation times, but in vivo functions as procoagulant. First described by C. Lockard Conley in 1952
Blood clot in dural venous sinuses or cerebral veins. Nine in ten patients experience severe headache. Around 40% develop seizures, especially in women. Focal neurological deficits occur in 50% of cases
Thrombolysis dissolves blood clots using medication. Used in myocardial infarction, stroke, and severe venous thromboembolism. Main complication is bleeding, which can be dangerous