Hypothalamus releases TRH, which triggers pituitary to produce TSH. TSH stimulates thyroid to release T4 and T3. T4 inhibits pituitary and hypothalamus in negative feedback loop
Carbimazole is a pro-drug converted to methimazole for hyperthyroidism treatment. Methimazole prevents thyroid peroxidase from coupling tyrosine residues. Treatment typically lasts 18-24 months followed by trial withdrawal. Rapid anti-thyroid effect onset, slower clinical hormone level effects
T3 test measures blood levels of thyroid hormone triiodothyronine (T3). Thyroid gland produces T3 and T4 hormones controlling energy use. Blood contains both free (active) and bound (protein-attached) T3 forms
Thyroid gland is a butterfly organ located above collarbone. Hormones T3, T4, calcitonin and iodine control vital body functions. Normal hormone levels must be maintained for proper functioning
Thyroid gland is located below Adam's apple, wrapped around trachea. Produces hormones regulating metabolism, heart rate, and temperature. Uses iodine to produce thyroxine (T4) and triiodothyronine (T3)
Free T3 test measures triiodothyronine hormone levels in blood. Thyroid gland produces both T3 and thyroxine (T4) hormones. Three types: free, bound, and total T3 tests