Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). Approved by FDA in 1988 under trade name Voltaren. Inhibits cyclooxygenase-1 and -2 enzymes, reducing prostaglandin production. Used for treating osteoarthritis, rheumatoid arthritis, and pain
Diclofenac is a COX-2 selective NSAID with potent analgesic effects. Rapidly absorbed orally, with peak serum concentrations in 2-3 hours. Highly bound to plasma proteins with volume of distribution of 0.12 L/kg. Excreted primarily in urine (65%) and as bile conjugates (35%)
Five different Voltaren gel products available for muscle and joint pain relief. All products contain diclofenac for pain relief and inflammation reduction
Cataflam contains 25mg or 50mg diclofenac potassium in sugar-coated tablets. Used for short-term treatment of pain, inflammation and swelling. Approved for post-traumatic, postoperative pain and migraine attacks
Voltaren contains diclofenac sodium in 25mg, 50mg, and 75mg enteric-coated tablets. Available only by prescription. Indicated for arthritis and pain relief
Cataflam contains 50 mg diclofenac potassium tablets for oral administration. Diclofenac has analgesic, anti-inflammatory and antipyretic properties. Mechanism involves inhibition of cyclooxygenase enzymes