Minimum age for Moderna/Pfizer-BioNTech: 6 months, Novavax: 12 years. Age 6-4 years: 2 Moderna doses, 3 Pfizer-BioNTech doses. Age 5-11 years: 1 Moderna/Pfizer-BioNTech dose. Age 12-18 years: 1 Moderna/Pfizer-BioNTech, 2 Novavax doses. Immunocompromised: 4 doses for age 6-4 years, 4 doses for age 5-11 years
mRNA is a single-stranded RNA that transports genetic information from DNA to cytoplasm. RNA contains uracil instead of thymine and ribose sugar instead of deoxyribose. mRNA helps cells assemble proteins based on DNA instructions
Adenoviruses are non-enveloped DNA viruses discovered in 1953. More than 50 serotypes exist in humans, divided into 7 subgroups. Express both early and late genes for viral replication
ACIP unanimously recommended Merck's Capvaxive for adults 65+. Vaxelis vaccine added to American Indian/Alaska Native infant recommendation. Capvaxive protects against 21 pneumococcal serotypes in adults
DTaP vaccination required at 6 weeks, 4 years for Kinrix/Quadracel. Hepatitis A routine at 12 months, hepatitis B at birth. HPV vaccination recommended at 9 years. Influenza: 6 months (IIV), 2 years (LAIV4), 18 years (RIV4). Measles/mumps/rubella routine at 12 months
ACIP develops recommendations for vaccine and passive immunization use in US. Committee oversees disease control through vaccination guidelines