Treats various fungal infections including aspergillosis, blastomycosis, and coccidioidomycosis. Approved in US in 1992 and listed as essential medicine by WHO. Broad spectrum activity against Aspergillus, unlike fluconazole. Not recommended for meningitis treatment due to poor CSF penetration
Treats various fungal infections including vaginal yeast, systemic Candida, and Cryptococcal meningitis. Works by inhibiting fungal cell wall synthesis through lanosterol 14-α-demethylase inhibition. Shows fungistatic activity against multiple Candida species and Cryptococcus neoformans
Ketoconazole is an antifungal, antiandrogen, and antiglucocorticoid medication. Used for skin infections like tinea, candidiasis, and dandruff. Oral form used only for severe fungal infections when alternatives fail. Applied form treats excessive male-patterned hair growth in women
Topical antifungals treat fungal infections on skin, scalp, nails, vagina or mouth. Available in various forms including creams, gels, lotions, powders and sprays. Most drugs destroy fungal cell walls by inhibiting ergosterol production
Treats pityriasis versicolor, fungal nail infections, and ringworm. Available as oral tablets or topical cream/ointment. Cream/ointment should not be used for fungal nail infections. Discovered in 1991 and approved by FDA in 2007
Lulizol is a topical antifungal cream approved by FDA in 2013. Marketed under brand name Luzu in USA and Japan. Works by altering fungi cell membrane synthesis