Allergic rhinitis affects 10-20% of population, often goes undetected in primary care. Disorder affects both upper and lower respiratory tracts. Symptoms include nasal congestion, itching, rhinorrhea and sneezing
Bilastine is a second-generation H1-antihistamine approved for allergic rhinitis and urticaria. Rapidly absorbed with 60% oral bioavailability after 1 hour. Highly selective for H1 receptors, 3-6 times more potent than cetirizine
Beclometasone is available as inhaler, cream, pills, and nasal spray. Inhaled form treats long-term asthma management. Cream used for dermatitis and psoriasis. Pills treat ulcerative colitis. Nasal spray treats allergic rhinitis and nasal polyps
Treats asthma in patients 12 months and older. Prevents exercise-induced bronchoconstriction in patients 6 years and older. Relieves seasonal allergic rhinitis in patients 2 years and older
Hypersensitivity is an abnormal immune response to antigens. Gell and Coombs classified hypersensitivity into four types in 1963. About 15% of humans have at least one type during their lives
Cetirizine is a crystalline drug with molecular formula C21H25ClN2O3. Rapidly absorbed with peak concentration reached in about 1 hour. Mainly eliminated in urine, with 70-85% recovered in urine. Protein binding is 93% in therapeutic range