Rare disease causing vascular tumors leading to platelet count decrease. Named after Kasabach and Merritt, described in 1940. Usually affects infants under three months of age
FFP is a blood product made from whole blood's liquid portion. Contains water, proteins, carbohydrates, fats, and vitamins. Frozen plasma lasts about a year. First used in medical practice during WWII
ET is characterized by increased platelet count and megakaryocytic hyperplasia. Usually occurs after age 50, more common in females. Platelet count > 450,000/mcL is diagnostic criterion
Thrombocytosis occurs when blood platelets exceed 450,000 per microliter. Normal platelet count ranges from 150,000 to 450,000 per microliter
Purpura is a discolored spot on skin caused by leaking blood vessels. Appears purple on light skin, dark brown/black on dark skin. Can appear on skin or mucous membranes
Pancytopenia is low levels of all blood cell types in bone marrow. Includes anemia (low RBCs), leukopenia (low WBCs), and thrombocytopenia (low platelets). All blood cells originate from hematopoietic stem cells