M. genitalium is a small, sexually transmitted bacterium found in human urogenital tract. First isolated in 1981, identified as new species in 1983. Genome consists of 580,070 base pairs, making it one of smallest organisms. Can adhere to host cells using proteins P110 and P140
First synthesized in 1912, invented by A. Kachugin in 1949. First tested at Many Farms, Navajo community in Arizona. Initially used as antidepressant, discontinued in 1961 due to hepatotoxicity
CTVT is a sexually transmitted histiocytic tumor affecting canine genitalia. One of three known transmissible cancers in mammals. Genome diverged from canids over 6,000 years ago. First described by Russian veterinarian Novinsky in 1876
Aminoglycosides are traditional Gram-negative antibiotics containing amino-modified glycosides. Streptomycin is the first aminoglycoside, derived from Streptomyces griseus. Most aminoglycosides contain 2-deoxystreptamine moiety. Streptomyces-derived aminoglycosides end in -mycin, Micromonospora-derived with -micin
Penicillin was discovered by Fleming in 1928 from Penicillium notatum mold. Penicillin revolutionized bacterial infection treatment in 1941. Streptomycin was discovered in 1943 as effective against tuberculosis. Gramicidin and tyrocidin were discovered in 1939 by Dubos
Healthcare is an international, peer-reviewed, open access journal published semimonthly. Ranked Q2 in both Health Care Sciences and Leadership and Management. Impact Factor of 2.4 (2023) and 5-Year Impact Factor of 2.5 (2023). Manuscripts undergo peer-review within 20.5 days, publication acceptance in 2.7 days