Compression of left common iliac vein by right common iliac artery. Affects 2-5% of lower-extremity venous disorders. Three times more common in women than men. Typically presents in second to fourth decades of life
DVT is blood clot formation in deep veins, most commonly in legs or pelvis. Symptoms include pain, swelling, redness, and enlarged veins. Some DVTs may have no symptoms
Vascular disease affects blood vessels and lymphatic system. Coronary heart disease is leading cause of death in US. Arterial diseases involve blood supply obstruction. Venous diseases result from slow blood return or blood clots
Homans Sign was first described by John Homans in 1941. Test involves dorsiflexing foot with knee extended and flexed. Positive sign indicates deep vein thrombosis causing calf pain
Lixiana contains edoxaban tosylate, approved in EU on June 19, 2015. Used to prevent stroke and systemic embolism in atrial fibrillation patients. Treats and prevents DVT and pulmonary embolism in adults. Available as 15, 30, and 60 mg tablets, taken once daily
Atrial fibrillation: 60 mg daily for stroke prevention. DVT/PE: 60 mg daily after 5-10 days of parenteral anticoagulation. Weight-based dosing: 30 mg daily for patients under 60 kg