- Description and Mechanism
- Arveles is an isomer of ketoprofen with analgesic, anti-inflammatory and antipyretic properties
- Works by inhibiting cyclooxygenase pathway activity
- Onset is within 30 minutes, duration is 4-6 hours
- Dosage
- Adult dosage: 12.5 mg every 4-6 hours or 25 mg every 8 hours
- Maximum daily dose: 75 mg
- Elderly should start with 50 mg daily
- Not recommended for severe renal or hepatic impairment
- Side Effects
- Common: nausea, vomiting, diarrhea, stomach pain
- Uncommon: headache, dizziness, sleep disorders
- Rare: stomach ulceration, bleeding, high blood pressure
- Very rare: liver/renal damage, allergic reactions
- Contraindications
- Pregnancy and breastfeeding
- Children
- Active peptic ulcer or bleeding
- Severe heart failure
- Severe liver impairment
- Storage
- Store in cool, dry place
- Protect from light and moisture
- Keep out of reach of children