410 ile 12 kalibre arasındaki fark, namlu çaplarının farklı olmasıdır. - 410 kalibre, yaklaşık olarak 0,410 inç (10,4 mm) çapında bir namluya sahiptir. - 12 kalibre ise, 0,694 inç (17,6 mm) çapında bir namluya karşılık gelir.
12 kalibre, genellikle daha güçlü olarak kabul edilir çünkü daha büyük bir mermi boyutuna sahiptir. Ancak, bir merminin gücü sadece kalibresine değil, aynı zamanda kullanılan barut miktarına ve silahın tasarımına da bağlıdır.
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