Mardin'in en büyük mahallesi, 13 Mart Mahallesi'dir. Türkiye İstatistik Kurumu'nun 2018 yılı nüfus raporlarına göre, 13 Mart Mahallesi'nin nüfusu 24.376'dır.
Mardin'in merkez ilçeleri Artuklu ve Kızıltepe'dir. Artuklu, Mardin'in metropol ilçesidir. Kızıltepe, Artuklu, Mazıdağı ve Derik ilçeleri ile komşudur ve Şanlıurfa il sınırı ile Suriye sınırına yakındır.
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