İstanbul'daki en büyük han, Büyük Valide Han'dır 124.
Kösem Sultan tarafından 1651 yılında inşa ettirilen bu han, Çakmakçılar Yokuşu üzerinde yer alır ve üç avlusu vardır 125. İstanbul'un en büyük ticari hanı olarak bilinir 5.
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