Cehennem Melekleri 2 filminde yer alan bazı oyuncular şunlardır: Sylvester Stallone - Barney Ross; Jason Statham - Lee Christmas; Jet Li - Yin Yang; Dolph Lundgren - Gunnar Jensen; Bruce Willis - Mr. Church; Arnold Schwarzenegger - Trench; Terry Crews - Hale Caesar; Randy Couture - Toll Road; Liam Hemsworth - Billy the Kid; Yu Nan - Maggie.