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    • Yawiki ›
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    Sanger dizilemesi

    DNA Dizileme Yöntemi
    letgenbio.com sitesinden görsel
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    Yazeka

    Arama sonuçlarına dayanarak oluşturuldu

    Sanger dizilemesi, DNA'nın baz dizisini belirlemek için kullanılan zincir sonlandırma yöntemine dayanan bir tekniktir. 1977'de Frederick Sanger tarafından geliştirilmiş ve Nobel Kimya Ödülü ile taçlandırılmıştır.12

    Yöntem, DNA polimeraz enzimi ve floresan etiketli dideoksi nükleotidler kullanılarak DNA sentezinin rastgele sonlandırılmasına dayanır. Elde edilen parçalar elektroforez ile ayrılarak dizi belirlenir.23

    Yüksek doğruluk oranı ve uzun okuma uzunluklarıyla genom projelerinde temel oluşturmuştur. Günümüzde PCR sonuçlarının doğrulanması gibi alanlarda hala kullanılmaktadır.14

    drozdogan.com1
    insilicodesign.com2
    tr.wikipedia.org3
    acikders.ankara.edu.tr4

    Biyolojik teknikler ve araçlar

    DNA
    dizileme
    Polimeraz
    zincir reaksiyonu
    Southern
    blot
    DNA
    mikroçip
    Single-
    cell sequencing
    Genomic
    library
    ABO kan
    grubu sistemleri
    ELISA
    Yumurta
    Yanıt, yapay zeka tarafından internetteki kaynaklara dayanarak oluşturulmuştur. Hatalar içerebilir.
    Yazeka hakkındatr.wikipedia.org
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